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Cellular and Molecular Gastroenterology and Hepatology

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Issue cover for Volume 12, Issue 4

2021

Volume 12Issue 4p1179-1516

Open Access

Issue cover for Volume 12, Issue 4

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Editorials

IDO in Colorectal Tumorigenesis: Involvement of Immune Tolerance and Significance in Prevention and Therapy

Shunan Tang,
Jingya Wang,
Siwang Yu

Published online: July 16, 2021

p1503-1504

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GATA4 in Regional Affairs

Michael Paul Verzi

Published online: July 23, 2021

p1505-1506

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Wilson Disease: Epigenetic Factors Contribute to Genetic Mutations to Affect the Disease

Som Dev,

James P. Hamilton

Published online: August 02, 2021

p1507-1508

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When Pathobiont-Carbohydrate Interaction Turns Bittersweet!

Nicolas Barnich,

Benoit Chassaing

Published online: August 31, 2021

p1509-1510

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Reviews

Secretory Sorcery: Paneth Cell Control of Intestinal Repair and Homeostasis

Secretory Sorcery: Paneth Cell Control of Intestinal Repair and Homeostasis

Paul Cray,
Breanna J. Sheahan,
Christopher M. Dekaney

Published online: June 17, 2021

p1239-1250

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The Production and Function of Endogenous Interleukin-10 in Intestinal Epithelial Cells and Gut Homeostasis

The Production and Function of Endogenous Interleukin-10 in Intestinal Epithelial Cells and Gut Homeostasis

Huong D. Nguyen,
Hanan M. Aljamaei,
Andrew W. Stadnyk

Published online: July 13, 2021

p1343-1352

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Original Research

Blockade of IDO-Kynurenine-AhR Axis Ameliorated Colitis-Associated Colon Cancer via Inhibiting Immune Tolerance

Blockade of IDO-Kynurenine-AhR Axis Ameliorated Colitis-Associated Colon Cancer via Inhibiting Immune Tolerance

Xin Zhang,
Xiuting Liu,
Wei Zhou,
...
Mengdi Yang,
Yang Ding,
Rong Hu

Published online: May 31, 2021

p1179-1199

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6-Gingerol Ameliorates Hepatic Steatosis via HNF4α/miR-467b-3p/GPAT1 Cascade

6-Gingerol Ameliorates Hepatic Steatosis via HNF4α/miR-467b-3p/GPAT1 Cascade

Jiyun Ahn,
Hyunjung Lee,
Chang Hwa Jung,
...
Hyo-Deok Seo,
Young In Kim,
Taeyoul Ha

Published online: June 14, 2021

p1201-1213

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Supplemental Materials

Enteric Glia Regulate Lymphocyte Activation via Autophagy-Mediated MHC-II Expression

Enteric Glia Regulate Lymphocyte Activation via Autophagy-Mediated MHC-II Expression

Aaron K. Chow,
Vladimir Grubišić,
Brian D. Gulbransen

Published online: June 21, 2021

p1215-1237

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Prebiotic Enriched Exclusive Enteral Nutrition Suppresses Colitis via Gut Microbiome Modulation and Expansion of Anti-inflammatory T Cells in a Mouse Model of Colitis

Prebiotic Enriched Exclusive Enteral Nutrition Suppresses Colitis via Gut Microbiome Modulation and Expansion of Anti-inflammatory T Cells in a Mouse Model of Colitis

Genelle R. Healey,
Kevin Tsai,
Alana Schick,
...
Laura Cook,
Bruce A. Vallance,
Kevan Jacobson

Published online: June 29, 2021

p1251-1266

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Ileal Derived Organoids From Crohn’s Disease Patients Show Unique Transcriptomic and Secretomic Signatures

Ileal Derived Organoids From Crohn’s Disease Patients Show Unique Transcriptomic and Secretomic Signatures

Barbara Joanna Niklinska-Schirtz,
Suresh Venkateswaran,
Murugadas Anbazhagan,
...
Anil G. Jegga,
Jason D. Matthews,
Subra Kugathasan

Published online: July 13, 2021

p1267-1280

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Acute Experimental Barrier Injury Triggers Ulcerative Colitis–Specific Innate Hyperresponsiveness and Ulcerative Colitis–Type Microbiome Changes in Humans

Acute Experimental Barrier Injury Triggers Ulcerative Colitis–Specific Innate Hyperresponsiveness and Ulcerative Colitis–Type Microbiome Changes in Humans

Jakob Benedict Seidelin,
Martin Iain Bahl,
Tine Rask Licht,
...
Marina Ramírez Galera,
Anders Woetmann,
Jacob Tveiten Bjerrum

Published online: June 09, 2021

p1281-1296

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Fatty Acids Activate the Transcriptional Coactivator YAP1 to Promote Liver Fibrosis via p38 Mitogen-Activated Protein Kinase

Fatty Acids Activate the Transcriptional Coactivator YAP1 to Promote Liver Fibrosis via p38 Mitogen-Activated Protein Kinase

Shadi Salloum,
Andre J. Jeyarajan,
Annie J. Kruger,
...
Nadia Alatrakchi,
Esperance A.K. Schaefer,
Raymond T. Chung

Published online: June 09, 2021

p1297-1310

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Lactobacillus rhamnosus GG Orchestrates an Antitumor Immune Response

Lactobacillus rhamnosus GG Orchestrates an Antitumor Immune Response

Joshua A. Owens,
Bejan J. Saeedi,
Crystal R. Naudin,
...
Trevor M. Darby,
Brian S. Robinson,
Rheinallt M. Jones

Published online: June 06, 2021

p1311-1327

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Serum Amyloid A Promotes Inflammation-Associated Damage and Tumorigenesis in a Mouse Model of Colitis-Associated Cancer

Serum Amyloid A Promotes Inflammation-Associated Damage and Tumorigenesis in a Mouse Model of Colitis-Associated Cancer

Tanja A. Davis,
Daleen Conradie,
Preetha Shridas,
Frederick C. de Beer,
Anna-Mart Engelbrecht,
Willem J.S. de Villiers

Published online: July 01, 2021

p1329-1341

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Aberrant Epithelial Differentiation Contributes to Pathogenesis in a Murine Model of Congenital Tufting Enteropathy

Aberrant Epithelial Differentiation Contributes to Pathogenesis in a Murine Model of Congenital Tufting Enteropathy

Barun Das,
Kevin Okamoto,
John Rabalais,
Jocelyn A. Young,
Kim E. Barrett,
Mamata Sivagnanam

Published online: June 28, 2021

p1353-1371

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Enterococcus faecalis Glucosamine Metabolism Exacerbates Experimental Colitis

Enterococcus faecalis Glucosamine Metabolism Exacerbates Experimental Colitis

Ting-Jia Fan,
Laura Goeser,
Kun Lu,
Jeremiah J. Faith,
Jonathan J. Hansen

Published online: July 07, 2021

p1373-1389

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GATA4 Controls Epithelial Morphogenesis in the Developing Stomach to Promote Establishment of Glandular Columnar Epithelium

GATA4 Controls Epithelial Morphogenesis in the Developing Stomach to Promote Establishment of Glandular Columnar Epithelium

Ann DeLaForest,
Bridget M. Kohlnhofer,
Olivia D. Franklin,
...
Kirthi Pulakanti,
Sridhar Rao,
Michele A. Battle

Published online: June 06, 2021

p1391-1413

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Impaired Luminal Control of Intestinal Macrophage Maturation in Patients With Ulcerative Colitis During Remission

Impaired Luminal Control of Intestinal Macrophage Maturation in Patients With Ulcerative Colitis During Remission

Lujain Maasfeh,
Anetta Härtlova,
Stefan Isaksson,
...
Hans Strid,
Lena Öhman,
Maria K. Magnusson

Published online: June 11, 2021

p1415-1432

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ANKRD22 Drives Rapid Proliferation of Lgr5+ Cells and Acts as a Promising Therapeutic Target in Gastric Mucosal Injury

ANKRD22 Drives Rapid Proliferation of Lgr5⁺ Cells and Acts as a Promising Therapeutic Target in Gastric Mucosal Injury

Jingwen Liu,
Jingni Wu,
Rui Wang,
...
Hongping Wang,
Zhenya Song,
Yongliang Zhu

Published online: July 01, 2021

p1433-1455

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Wilson Disease: Intersecting DNA Methylation and Histone Acetylation Regulation of Gene Expression in a Mouse Model of Hepatic Copper Accumulation

Wilson Disease: Intersecting DNA Methylation and Histone Acetylation Regulation of Gene Expression in a Mouse Model of Hepatic Copper Accumulation

Gaurav V. Sarode,
Kari Neier,
Noreene M. Shibata,
...
Matthew L. Settles,
Janine M. LaSalle,
Valentina Medici

Published online: June 04, 2021

p1457-1477

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PIR-B Regulates CD4+ IL17a+ T-Cell Survival and Restricts T-Cell–Dependent Intestinal Inflammatory Responses

PIR-B Regulates CD4⁺ IL17a⁺ T-Cell Survival and Restricts T-Cell–Dependent Intestinal Inflammatory Responses

Jazib Uddin,
Sunil Tomar,
Ankit Sharma,
...
Senad Divanovic,
Ariel Munitz,
Simon P. Hogan

Published online: July 06, 2021

p1479-1502

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Research Letters

A Novel Noninvasive Method Based on Salivary Inflammatory Biomarkers for the Screening of Celiac Disease

A Novel Noninvasive Method Based on Salivary Inflammatory Biomarkers for the Screening of Celiac Disease

M. Sebastian-delaCruz,
A. Olazagoitia-Garmendia,
A. Huerta Madrigal,
...
L. Bujanda,
J.R. Bilbao,
A. Castellanos-Rubio

Published online: May 29, 2021

p1511-1513.e2

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Gut ACE2 Expression, Tryptophan Deficiency, and Inflammatory Responses The Potential Connection That Should Not Be Ignored During SARS-CoV-2 Infection

Gut ACE2 Expression, Tryptophan Deficiency, and Inflammatory Responses The Potential Connection That Should Not Be Ignored During SARS-CoV-2 Infection

W.-H. Qin,
C.-L. Liu,
Y.-H. Jiang,
B. Hu,
H.-Y. Wang,
J. Fu

Published online: June 30, 2021

p1514-1516.e4

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Frontmatter

Editorial Board

Published in issue: 2021

A1

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Contents

Published in issue: 2021

A2-A5

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Elsewhere in the AGA Journals

Published in issue: 2021

A6-A9

PDF

Cover 1 - GATA4 Controls Gastric Columnar Epithelial Cell Development

Published in issue: 2021

OFC

PDF

Cover 2 - Disrupted Brush Border in Congenital Tufting Enteropathy

Published in issue: 2021

IFC

PDF

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