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Basic and Translational Advances in Epithelial and Stem Cell Biology

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Original Research
Open Access
Environmental Enteric Dysfunction Includes a Broad Spectrum of Inflammatory Responses and Epithelial Repair Processes
Cellular and Molecular Gastroenterology and Hepatology
Vol. 2Issue 2p158–174.e1Published online: December 11, 2015
- Jinsheng Yu
- M. Isabel Ordiz
- Jennifer Stauber
- Nurmohammad Shaikh
- Indi Trehan
- Erica Barnell
- and others
Cited in Scopus: 46
Environmental enteric dysfunction (EED), a chronic diffuse inflammation of the small intestine, is associated with stunting in children in the developing world. The pathobiology of EED is poorly understood because of the lack of a method to elucidate the host response. This study tested a novel microarray method to overcome limitation of RNA sequencing to interrogate the host transcriptome in feces in Malawian children with EED.